Nicholas Schafer

Postdoc
Department:

I’m currently working on developing computational and experimental techniques for probing membrane protein folding and stability.

Publications list

Parra RG; Schafer NP; Radusky LG; Tsai MY; Guzovsky AB; Wolynes PG; Ferreiro DU, 2016. Protein Frustratometer 2: a tool to localize energetic frustration in protein molecules, now with electrostatics.  Nucleic Acids Res.

Tsai MY; Zheng W; Balamurugan D; Schafer NP; Kim BL; Cheung MS; Wolynes PG, 2016. Electrostatics, structure prediction, and the energy landscapes for protein folding and binding.  Protein Sci 25(1):255-69

Schafer NP; Truong HH; Otzen DE; Lindorff-Larsen K; Wolynes PG, 2016. Topological constraints and modular structure in the folding and functional motions of GlpG, an intramembrane protease.  Proc Natl Acad Sci U S A 113(8):2098-103

Paslawski W; Lillelund OK; Kristensen JV; Schafer NP; Baker RP; Urban S; Otzen DE, 2015. Cooperative folding of a polytopic α-helical membrane protein involves a compact N-terminal nucleus and nonnative loops.  Proc Natl Acad Sci U S A 112(26):7978-83

Sirovetz BJ; Schafer NP; Wolynes PG, 2015. Water Mediated Interactions and the Protein Folding Phase Diagram in the Temperature-Pressure Plane.  J Phys Chem B 119(34):11416-27

Truong HH; Kim BL; Schafer NP; Wolynes PG, 2015. Predictive energy landscapes for folding membrane protein assemblies.  J Chem Phys 143(24):243101

Kim BL; Schafer NP; Wolynes PG, 2014. Predictive energy landscapes for folding α-helical transmembrane proteins.  Proc Natl Acad Sci U S A 111(30):11031-6

Morcos F; Schafer NP; Cheng RR; Onuchic JN; Wolynes PG, 2014. Coevolutionary information, protein folding landscapes, and the thermodynamics of natural selection.  Proc Natl Acad Sci U S A 111(34):12408-13

Schafer NP; Kim BL; Zheng W; Wolynes PG, 2014. Learning To Fold Proteins Using Energy Landscape Theory.  Isr J Chem 54(8-9):1311-1337

Truong HH; Kim BL; Schafer NP; Wolynes PG, 2013. Funneling and frustration in the energy landscapes of some designed and simplified proteins.  J Chem Phys 139(12):121908

Zheng W; Schafer NP; Wolynes PG, 2013. Frustration in the energy landscapes of multidomain protein misfolding.  Proc Natl Acad Sci U S A 110(5):1680-5

Zheng W; Schafer NP; Wolynes PG, 2013. Free energy landscapes for initiation and branching of protein aggregation.  Proc Natl Acad Sci U S A 110(51):20515-20

Davtyan A; Schafer NP; Zheng W; Clementi C; Wolynes PG; Papoian GA, 2012. AWSEM-MD: protein structure prediction using coarse-grained physical potentials and bioinformatically based local structure biasing.  J Phys Chem B 116(29):8494-503

Schafer NP; Hoffman RM; Burger A; Craig PO; Komives EA; Wolynes PG, 2012. Discrete kinetic models from funneled energy landscape simulations.  PLoS One 7(12):e50635

Zheng W; Schafer NP; Davtyan A; Papoian GA; Wolynes PG, 2012. Predictive energy landscapes for protein-protein association.  Proc Natl Acad Sci U S A 109(47):19244-9

Publication list retrieved from NCBI using ImpactPubs

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